www.carleton.ca

 

 



Research Interests
» Kindling
» Genetics
» Status epilepticus
» Neuroprotection
» Stimulation

Recent Publications:
» Refereed papers
» Book chapters
» Conferences &
Abstracts


Professional
Activities & Grants


Refereed papers

2004 / 2003 / 2002 / 2001 / 2000 / 1999

Xu, B., Fahnestock, M., McIntyre, D.C. and Racine, R.J. (2004) Strain differences affect in induction of status epilepticus and seizure-induced morphological changes. European Journal of Neuroscience (in press)

Reinhart, C.J., McIntyre, D.C. and Pellis, S.M. (2004) The development of play fighting in kindling-prone (FAST) and kindling–resistant (SLOW) rats: How does the retention of phenotypic juvenility affect the complexity of play? Developmental Psychobiology (in press)

Shin, R. Merali, Z., Anisman, H. and McIntyre, D.C. (2004) Amygdala amino acid and monoamine levels in genetically fast and slow kindling rat strains during massed amygdala kindling. European Journal of Neuroscience (in press)

Foster, J.A., Puchowicz, M.J., McIntyre, D.C. and Herkenham, M. (2004) Activin mRNA induced during amygdala kindling shows a spatiotemporal progression that tracks the spread of seizures. J. Comparative Neurology (in press)

McIntyre, D.C., McLeod, W. and Anisman, H. (2004) Working and reference memory in seizure-prone and seizure-resistant rats: Impact of amygdala kindling. Behavioral Neuroscience. (in press)

McIntyre, D.C. (2004) Kindling. Encyclopedia of Neuroscience. 3; 1-3 (in press)

Flynn, C., Monfils, M-H., Kleim, J.A., Kolb, B., McIntyre, D.C., and Teskey, G.C. (2004) Differential neuroplastic changes in neocortical movement representations and dendritic morphology in epilepsy-prone and epilepsy-resistant rat strains following high-frequency stimulation. European J. Neuroscience (in press)

Gilby K.L., Goncalves da Silva A. and McIntyre D.C. (2004) Differential GABAA subunit expression following status epilepticus in seizure-prone and seizure-resistant rats: A putative mechanism for refractory behavior. Epilepsy Res. (in press)

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Racine, R.J., Steingart, M. Bureau, Y. and McIntyre, D.C. (2003) Differential sensitivity of genetically Fast versus Slow Kindling rats strains to GABAergic convulsive agents. Neuropharmacology. 45(7): 918-924.

Kelly, O.P., McIntosh,J., McIntyre, D.C., Merali, Z. and Anisman, H . (2003) Anxiety in rats selectively bred for fast and slow kindling rates: situation-specific outcomes. Stress 6: 289-295.

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Anisman, H, and McIntyre, D.C. (2002) Conceptual, spatial and cue learning in the Morris water-maze in Fast or Slow kindling rats: attention deficit comorbidity. Journal of Neuroscience. 22(17): 7809-7817.

McIntyre, D.C., Hutcheon, B., Schwabe, K. and Poulter, M.O. (2002) Divergent
GABAA receptor mediated synaptic transmission in genetically seizure-prone and
seizure-resistant rats. Journal of Neuroscience. 22(22): 9922-9931.

Anisman, H. and McIntyre, D.C. (2002) Impulsivity and attention deficits in rats bred for seizure susceptibility. Iberoamericana de informacian cientifica. A4 1-6.

Shin, R. Merali, Z., Anisman, H. and McIntyre, D.C. (2002) Changes in extracellular levels of amygdala amino acids in genetically Fast versus Slow kindling rat strains. Brain Research, 946:31-42.

Kelly M.E., Staines, W.A. and McIntyre, D.C. (2002) Secondary generalization of
hippocampal kindled seizures: role of the piriform cortex. Brain Research 957:152-161.

McIntyre, D.C., Poulter, M.O. and Gilby, K. (2002) Kindling: some old some new. Epilepsy Research. 50: 79-92.

Coulter, D.A., McIntyre, D.C. and Löscher, W. (2002) Animal models of limbic epilepsy: What can they tell us? Brain Pathology, 12: 240-257.

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Merali, Z., Kent, P. Michaud, D., McIntyre, D.C. and Anisman, H. (2001) Differential impact of predator or immobilization stressors on central corticotropin-releasing hormone and bombesin-like peptides in Fast and Slow seizing rats. Brain Research. 906, 60-73.

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Anisman, H., Kelly, O., Hayley, S., Borowski, T. Merali, Z. and McIntyre,
D.C.
(2000) Acoustic startle and fear potentiated startle in rats
selectively bred for fast and slow kindling rates: Relation to monoamine
activity. European Journal of Neuroscience. 12, 4405-4416.

Plata-Salaman, C.R., Llyin, S.E., Turrin, N.P., Gayle, D., Flynn, M.C., Romanovitch,
A.E., Kelly, M.E., Bureau, Y., Anisman, H. and McIntyre, D.C.
(2000). Kindling modulates the IL-1ß system, TNF-a, TGF-ß1 and neuropeptide mRNAs in specific brain regions. Molecular Brain Research 75, 248-258.

McIntyre, D.C., Plant, J.R. and Kelly, M.E. (2000). Dorsal hippocampal kindling
produces long-lasting changes in the origin of spontaneous discharges in the piriform vs perirhinal cortex in vitro. Epilepsy Research 39, 191-200.

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McIntyre, D.C., Kent, P., Hayley, S., Merali, Z. and Anisman, H. (1999). Influence of psychogenic and neurogenic stressors on neuroendocrine and central neurotransmitter activity in Fast and Slow kindling rats. Brain Research 840, 65-74.

McIntyre, D.C., Kelly, M.E. and Dufresne, C. (1999). FAST and SLOW amygdala kindling rat strains: Comparison of amygdala, hippocampal piriform and perirhinal cortex kindling. Epilepsy Research 35, 197-209.

Racine, R.J., Steingart, M. and McIntyre D.C. (1999). Development of kindling-prone and kindling-resistant rats: Selective breeding and electrophysiological studies. Epilepsy Research 35, 183-195.

Poulter, M.O., Brown, L.A., Tynan, S., Willick, G., Williams, R and McIntyre D.C. (1999). Differential expression of a1, a2, a3, and a5 GABAA receptor subunits in seizure-prone and seizure-resistant rat models of temporal lobe epilepsy. Journal of Neuroscience 19, 4654-4661.

Xu, D., Bureau, Y., McIntyre, D.C., Nicholson, D.W., Liston, P., Zhu, Y., Korneluk, R.G. and Robertson, G.S. (1999). Attenuation of ischemia-induced cellular and behavioral deficits by X chromosome-linked inhibitor of apoptosis protein overexpression in the rat hippocampus. Journal of Neuroscience 19, 5026-5033.

Kelly, M.E., Battye, R.A. and McIntyre D.C. (1999). Cortical spreading depression reversibly disrupts convulsive motor seizure expression in amygdala kindled rats. Neuroscience 91, 305-313.

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