Refereed Publications

Al-aubidy, B., , Dias,A., Bain, R., Jafer, S., Dumontier, M., Wainer,G., and Cheetham, J. (2007) Advanced DEVS models with applications to biology and medicine. AIS 2007, Artificial Intelligence, Simulation and Planning. Buenos Aires, Argentina. .

Pitre S, Dehne F, Chan A, Cheetham J, Duong A, Emili A, Gebbia M, Greenblatt J, Jessulat M, Krogan N, Luo X, Golshani A. , (2006) PIPE: a protein-protein interaction prediction engine based on the re-occurring short polypeptide sequences between known interacting protein pairs, BMC Bioinformatics, 7, 365.

Murray, J., Cuccia, L., Ianoul, A., Cheetham, J.J. and Johnston, L.J. (2004) Imaging the Selective Binding of Synapsin to Anionic Membrane Domains, ChemBioChem, 5, 1-7.

Hurley, S.L., Brown, D.L. and Cheetham, J.J. (2004) Cytoskeletal Interactions of Synapsin I in Non-Neuronal Cells, Biochem. Biophys. Res. Comm., 317, 16-23.

Cheetham, J.J., Murray, J., Ruhkalova, M., Cuccia, L., McAloney, R., Ingold, K.U. and Johnston, L.J. (2003) Interaction of synapsin I with membranes, Biochem. Biophys. Res. Comm., 309, 823 -829.

Cheetham,J.J., Dehne, F., Pitre, S., Rau-Chaplin, A., and Taillon, P.J. (2003) Parallel CLUSTAL W For PC Clusters, Proc. International Conference on Computational Science and Its Applications (ICCSA 2003), Montreal, Canada, May 18-21, 2003.

Cheetham, J.J., Dehne, F., Rau-Chaplin, A., Stege, U., Taillon, P.J. (2003) Solving Large FPT Problems on Course Grained Parallel Machines, J. Comp. Sys. Sci. (in press).

Cheetham, J.J., Dehne, F., Rau-Chaplin, A., Stege, U., and Taillon,P. J., (2003) A Parallel FPT Application For Clusters, Proc. 3rd IEEE/ACM International Symposium on Cluster Computing and the Grid (CCGrid 2003).

Cheetham, J.J., Weber T., Hilfiker-Rothenfluh, S., Benfenati, F., Brunner, J., Czernik, A.J. and Greengard, P. (2001) Identification of Domain C Peptide Sequences of Synapsin I that Insert into Lipid Membranes, Biochemical J., 354, 57-66.

McManus, G., Buchanan, G., Jarrel, H., Epand, R.M., Epand, R. and Cheetham, J.J. (2001) Membrane Perturbing Properties of Sucrose Polyesters, Chem. Phys. Lipids, 109, 185- 202.

Cross, A.R., McPhee, D., Stevens, D., McDonald, M., Cheetham, J.J., and Santyr, G.E. (2000) Hyperpolarized Xenon Relaxation Times in Perfluorocarbon Emulsion and Plasma Mixtures, Proceedings of the World Congress on Medical Imaging, 101-102.

Boudreau, R., Carmody, G. and Cheetham, J.J. (1999) Pareto Analysis of Paleontological Data: A New Method of Weighing Variable Importance, Paleontologica Electronica, 2, 1-6.

Zambrano, N., Buxbaum, J.D., Minopoli, G., Fiore, F., De Candia, P., De Renzis, S., Faraonio, R., Sabo, S., Cheetham, J.J., Sudol, M. and Russo, T. (1997) Interaction of the Phosphotyrosine Interaction/Phosphotyrosine Binding Domains of Fe65 with Wild-Type and Mutant Alzheimer's ß-Amyloid Precursor Proteins, J. Biol. Chem., 272, 6399-6405.

Desdouits, F., Cheetham. J.J., Huang, H.-B., Kwon, Y.-S., da Cruz e Silva, E.F., Denefle, P., Ehrlich, M.E., Nairn, A.C., Greengard, P. and Girault, J.-A. (1995) Mechanism of Inhibition of Protein Phosphatase 1 by DARPP-32: Studies with Recombinant DARPP- 32 and Synthetic Peptides (1995) Biochem. Biophys. Res. Comm., 206, 652-658.

Van Gorkom, L.C.M., Cheetham, J.J. and Epand, R.M., Ganglioside GD1a Generates Domains of High Curvature in Phosphatidylethanolamine Liposomes as Determined by Solid State 31P NMR Spectroscopy, (1995) Chem. Phys. Lipids, 76, 103-108.

Cheetham, J.J., Nir, S., Johnson, E., Flanagan, T.D. and Epand, R.M., The Effects of Membrane Physical Properties on the Fusion of Sendai Virus with Human Erythrocyte Ghosts and Liposomes: Analysis of the Kinetics and Extent of Fusion (1994) J. Biol. Chem., 269, 5467- 5472.

Epand, R.M., Cheetham, J.J., Epand, R.F., Yeagle, P., Richardson, C., Rockwell, A. and DeGrado, W.F., Peptide Models for the Membrane Destabilizing Actions of Viral Fusion Proteins, (1992) Biopolymers, 32, 309-314.

Cheetham, J.J., Chen, R.J.B. and Epand, R.M., Interaction of Calcium and Cholesterol Sulphate Induces Membrane Destabilization and Fusion: Implications for the Acrosome Reaction (1990) Biochim. Biophys. Acta, 1024, 367-372.

Cheetham, J.J., Andrews, M, Epand, R.M. and Flanagan, T.D., Cholesterol Sulphate Inhibits the Fusion of Sendai Virus to Biological and Model Membranes (1990) J. Biol. Chem., 265, 12404-12409.


Cheetham, J.J., Epand, R.M., Bach, D. and Wachtel, E., Role of the Stereochemistry of the Hydroxyl Group of Cholesterol and the Formation of Nonbilayer Structures in Phosphatidylethanolamines (1989) Biochemistry, 28, 8928-8934.

Epand, R.M., Stafford, A.R., Cheetham, J.J., Bottega, R. and Ball, R.H., The Relationship Between the Bilayer to Hexagonal Phase Transition Temperature in Membranes and Protein Kinase C Activity (1988) Biosci. Rep., 8, 49-54.

Epand, R.M., Cheetham, J.J. and Raymer, K.E., Acid-Induced Fusion of Liposomes: Studies with 2,3-Seco-5a-Cholestan-2,3-Dioic Acid (1988) Biochim. Biophys. Acta, 940, 85-92.

Cheetham, J.J. and Epand, R.M., Comparison of the Interaction of the Anti-Viral Chemotherapeutic Agents Amantadine and Tromantadine with Model Phospholipid Membranes (1987) Biosci. Rep., 7, 225-230.

Full Length Papers: in preparation

Hurley, S., Brown, D. and Cheetham, J.J. (2003) Cytoskeletal Interactions of Synapsin I in Non-
Neuronal Cells (in revision).

McPhee, D., Johnson, B., and Cheetham, J.J. (2003) Disruption of Yeast using High Pressure Homogenization.

Cheetham, J.J., Murray, J., Dulubova, M., Cuccia, L. and Johnston, L. (2003) Stabilization of Membranes by Synapsin I.

Papers presented at scientific meetings

Johnston, L., Ianoul, A., Murray, J., and Cheetham, J.J. (2003) Near-Field Scanning Optical Microscopy Studies of Proteins in Model Membranes, Biophysical Society 47th Annual General Meeting, March 1-5, 2003, San Antonio, Texas, USA.

Cheetham, J.J., Dehne, F., Rau-Chaplin, A., Stege, U., and Taillon,P. J., (2003) A Parallel FPT Application For Clusters, Proc. 3rd IEEE/ACM International Symposium on Cluster Computing and the Grid (CCGrid 2003), Tokyo, Japan, May 12-15, 2003.

Cheetham, J.J., Murray, J., Dulubova, M., Cuccia, L. and Johnston, L. (2002) Stabilization of Membranes by Synapsin I. Membrane Biology Meeting, University of Montreal, Montreal, Quebec, Canada.

Cross, A.R., Santyr, G.E., McPhee, D., Wallace, J., Cheetham, J.J. and Cron, G. (2001) Effects of Dilution and Oxygenation on T1 of Hyperpolarized 129 Xe in Perfluorocarbon Emulsions, International Society for Magnetic Resonance Imaging, Edinburgh, Scotland.

Hurley, S., Brown, D. and Cheetham, J.J. (2000) Synapsin I-Green Fluorescent Fusion Protein Binds to Actin in Non-Neuronal Cells, American Association of Cell Biology, Annual Meeting, San Francisco, CA.

Cross, A.R., McPhee, D., Stevens, D., McDonald, M., Cheetham, J.J. and Santyr, G.E., (2000) Hyperpolarized 129Xe T1 Relaxation in Perfluorocarbon Emulsion and Plasma Mixtures, American Society for Magnetic Resonance Meeting, Chicago IL, USA.

Hurley, S., Brown, D. and Cheetham, J.J. (1999) Expression of Synapsin I-Green Fluorescent Fusion Protein in Non-Neuronal Cells, Ottawa Life Sciences National Conference and Exhibition, Ottawa, Canada.

Hurley, S., Cull, J., Peel, M. and Cheetham, J.J. (1998) A Continuous Process for Production of Liposmes, Ottawa Life Sciences National Conference and Exhibition, Ottawa, Canada.

Hurley, S.,Cull, J., Peel, M. and Cheetham, J.J. (1998) Disruption of Yeast using High Pressure Homogenization, Ottawa Life Sciences National Conference and Exhibition, Ottawa, Canada.

Hughes, S.R., Watanabe, T., Buxbaum, J.D., Cheetham, J.J., Greengard, P., Riedel, N.G. and Sahasrabudhe, S.R. ß-Amyloid Peptide Interacts with a-Tubulin In Vivo (1996) Society for Neuroscience, 26th. Annual Meeting, Washington, DC.

Cheetham, J.J., McPherson, P.S., Wagg, J., Czernik, A.J., E.F. da Cruz e Silva, De Camilli, P., Schlessinger, J. and Greengard, P. Kinetics of Grb2 Binding to Synapsin I, (1995) Society for Neuroscience, 25th. Annual Meeting, San Diego, CA.

Sweeney, D., Zhou, Z., Martins, R., LeVine, H., Cheetham, J.J., Breslow, J., Smith J., Greengard, P. and Gandy, S. Physiological Apolipoprotein E e3 and e4 Isoforms Promote Fibrillogenesis of Aß (1-42) in a Thioflavine T Assay, (1995) Society for Neuroscience, 25th. Annual Meeting, San Diego, CA.

Hilfiker-Rothenfluh, S., Cheetham, J.J., Fienberg, A.A., Greengard, P. and Czernik, A.J., Interaction of Calcium Calmodulin-Dependent Protein Kinase II with Membranes: Studies with Purified Synaptic Vesicles and Liposomes (1994) Society for Neuroscience, 24th. Annual Meeting, Miami, FL.

Cheetham, J.J., Hilfiker-Rothenfluh, S., Czernik, A.J., Nairn, A.C. and Greengard, P., Identification of Phospholipid Binding Sites in Synapsin I Using Hydrophobic
Photoaffinity Labeling (1994) Society for Neuroscience, 24th. Annual Meeting, Miami, FL.

Cheetham, J.J., Huang, H.-B., da Cruz e Silva, E.F., Kwon, Y., Czernik, A.J., Nairn, A.C. and Greengard, P. Kinetics of Protein Phosphatase 1C Binding to Phospho-and Dephospho- DARRP 32, (1994) BIAsymposium, Fourth Annual Meeting, Baltimore, MD.

Van Gorkom, L.C.M., Cheetham, J.J. and Epand, R.M., Ganglioside GD1a Induces an Isotropic Phase in Phosphatidylethanolamines as Measured by 31P NMR (1991) Biophysical Journal, 59, 313a.

Cheetham, J.J., Van Gorkom, L.C.M., Flanagan, T.D. and Epand, R.M., Bilayer Stabilizers Inhibit Sendai Virus Fusion at Neutral pH But Not Acid-Induced Fusion of Influenza Virus (1991) Biophysical Journal, 59, 132a.

Epand, R.M., Cheetham, J.J., Epand, R.F., Peptide Models for the Membrane Destabilizing Actions of Viral Fusion Proteins (1991) The Peptide-Protein Bridge Conference, Toronto, Ontario, Canada.

Cheetham, J.J., Flanagan, T.D. and Epand, R.M., Inhibition of Virus Fusion to Biological and Model Membranes by Bilayer Stabilizing Molecules (1990) Biophysical Journal, 57, 491a.

Epand, R.M., Cheetham, J.J. and Bottega, R., Substances Which Affect the Bilayer to Hexagonal Phase Transition Temperature and Their Effect on Membrane Fusion (1988) Biochemistry, 27, 3083.

Cheetham, J.J., Epand, R.M. and Flanagan, T.D., Substances Which Stabilize the Bilayer Phase of Membranes can Inhibit Membrane Fusion, (1988) FASEB Summer Research Conference on Structure and Function of Membranes.

Epand, R.M., Cheetham, J.J., Bottega, R., Wachtel, E.J. and Bach, D., The Effects of Cholesterol and Epicholesterol on the Phase Behavior of Phosphatidylethanolamines, (1988) FASEB Summer Research Conference on Structure and Function of Membranes.

Non-refereed publications and technical documents:

Kumar, P., Cheetham, J.J., Vierula, J. (2000) A Survey of Non-living Biotechnology R&D in Canada for The Canadian Space Agency. Contract # 9F007-0-1122.

Cheetham, J.J. and McPhee, D. (1998) Efficient disruption of E.coli using the EmulsiFlex C5, Avestin Inc. Technical Bulletin.

Cheetham, J.J., Stewart, A., Hurley, S., McPhee, D. (1998) High volume disruption of three yeasts using the EmulsiFlex C160, Avestin Inc. Technical Bulletin.

E-mail: jcheetha@ccs.carleton.ca