STOREY LAB MEMBERS - PRESENT AND PAST

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Current graduate students

Thesis topic & selected publications

Neal Dawson
Ryan Bell

Kyle Biggar

Jing Zhang

Shannon Tessier

Allan Letourneau
Mike
Wu

Yulia Maistrovski
Brian
Luu

Regulation of antioxidant enzymes in freeze tolerant wood frogs (1) | (2) | (3)
Enzymatic regulation in hibernation (1) | (2) | (3)
Transcription factor and microRNA regulation of gene expression in anoxia tolerant turtles. (1) | (2) | (3)
Regulation of anoxia-responsive gene expression in turtles. (1) | (2) | (3)
Transcription factors and control of hibernator muscle proteins. (1) | (2) | (3)
Enzymatic regulation in hibernation. (1) | (2) | (3)
Mechanisms of transcriptional control in mammalian hibernation (1) | (2) | (3)
Regulation of immune peptides in freeze tolerant wood frogs (1) | (2) | (3)
Novel freeze responsive proteins in wood frogs (1) | (2) | (3)

VIEW ABSTRACTS OF POSTER PRESENTATIONS AT SCIENTIFIC MEETINGS BY CURRENT AND RECENT GRAD STUDENTS

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Former post-doctoral fellows

Interests & selected publications

Where are they now?

Marina Batrukova

Ion motive ATPases & mammalian hibernation

Researcher, Moscow State University

Isabelle Moineau

Protein phosphatases

Research scientist, France

Qinyin Cai

Stress-induced gene expression. (1) | (2) | (3)

President, BioS&T Co., Lachine  

Craig Frank

Hibernator metabolism. (1) | (2) | (3)

Assoc. Prof., Fordham U., NY | webpage

Marcelo Hermes-Lima

Antioxidant defenses. (1) | (2) | (3)

Assoc. Prof., U. Brasilia, Brazil |

Stephen Brooks

Metabolic regulation. (1) | (2) | (3)

Research Scientist, Health Canada | webpage 1 | webpage 2

Basile Michaelidis

Enzyme control in anoxia tolerant molluscs. (1) | (2) | (3)

Researcher, Thessaloniki U., Greece

Ralph Ferguson

Intermediary metabolism in fish. (1) | (2) | (3)

Clinical pharmacologist, Toronto

Jim Ballantyne

Mitochondrial metabolism. (1) | (2) | (3)

Assoc. Prof, U. Guelph | webpage

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Former Ph.D. students

Thesis title and abstract, Selected publications

Where are they now?

Benjamin Lant, Ph.D. Biology 2011

The anoxia tolerant crayfish: a profile of stress response. Abstract   (1) | (2) | (3)

Post-doctoral fellow, Hospital for Sick Children, Toronto

Anastasia Krivoruchko, Ph.D. Biology 2010

Turtle anoxia - biochemistry and gene regulation in an anaerobic extremist. Abstract   (1) | (2)  | (3)

Post-doctoral fellow, Chalmers University of Technology, Gothenburg, Sweden

Amal Malik, Ph.D. Biology 2009

Cellular adaptation to dehydration stress: Molecular adaptations for dehydration tolerance in the African clawed frog, Xenopus laevis. Abstract   (1) | (2)  | (3)

Post-doctoral fellow, Health Canada, Ottawa

Christopher Dieni, Ph.D. Chemistry 2008

Regulation of enzyme function in freeze tolerance. Abstract   (1) | (2)  | (3)

Post-doctoral fellow, Micropharma Corp, Montreal

Khalil Abnous, Ph.D. Chemistry 2007

Regulation of metabolic enzymes during hibernation in ground squirrels. Abstract   (1) | (2)  | (3)

Assistant Professor, Department of Medicinal Chemistry, Mashad University of Medical Sciences, Mashad, Iran

Hapsatou Mamady, Ph.D. Biology 2006

Mammalian hibernation: gene expression and transcription factor regulation of the unfolded protein response, apoptosis and atrophy in ground squirrels. Abstract   (1) | (2) | (3)

Research Associate, Children’s Hospital of Eastern Ontario, Ottawa

Chris Ramnanan, Ph.D. Biology 2006

Regulation of metabolism in estivating land snails: role of reversible protein phosphorylation. Abstract   (1) | (2) | (3)

Assistant Professor, Dept. Cellular Biology & Anatomy, Georgia Health Sciences University, Augusta, Georgia

Pier Morin, Ph.D. Chemistry 2006  webpage

Transcriptional regulation in the hibernating thirteen-lined ground squirrel, Spermophilus tridecemlineatus. Abstract   (1) | (2) | (3)

Assistant Professor, Dept. Chemistry & Biochemistry, University of Moncton, New Brunswick

Dave McMullen, Ph.D. Chemistry, 2004

Molecular and biochemical adaptations in two cold-hardy gall insects. Abstract (1) | (2) | (3)

Post-doctoral fellow, Dept. Neurology, Uniformed Services University of Health Sciences, Bethesda, MD

Amritha De Croos, Ph.D. Chemistry, 2003

Gene and protein regulation in liver of the freeze tolerant wood frog, Rana sylvatica. Abstract (1) | (2) | (3)

Scientist, Mt. Sinai Hospital, University of Toronto, Toronto

Sean Eddy, Ph.D. Chemistry, 2003

Hibernation and gene expression. Abstract (1) | (2) | (3)

Scientist, Compendia Biosciences, Ann Arbor, MI   A

Dayre McNally, Ph.D. Chemistry, 2002

Freezing survival and gene expression in wood frogs. Abstract (1) | (2) | (3)

Medical doctor

Kevin Larade, Ph.D. Biology, 2002.

Response to anoxia exposure by the marine snail, Littorina littorea: transcription and translation patterns of differentially expressed genes and proteins. Abstract | (1) | (2) | (3)

Laboratory Quality Manager, Crime Laboratory Unit, Boston Police Department, Boston, MA

Dustin Hittel, Ph.D. Biology 2001 | webpage

Physiological role of differentially expressed genes and their protein products in the hibernating 13-lined ground squirrel Spermophilus tridecemlineatus. Abstract | (1) | (2) | (3)

Assistant Professor, Dept. Kinesiology, University of Calgary

Tammy English, Ph.D. Biology 2000.

Differential gene expression in response to freezing and anoxia in the intertidal marine gastropod, Littorina littorea. Abstract | (1)

Research grant development advisor, Vancouver Coastal Health Research Institute.

Andreas Fahlman, Ph.D. Biology 2000.

Physiology of hydrogen diving and implication for hydrogen biochemical decompression. Abstract | (1)

Assistant Professor, Department of Life Sciences, Texas A&M University, Corpus Christi, Texas

Shaobo Wu, Ph.D. Biology 1999.

Differential gene expression under environmental stress in the freeze tolerant wood frog, Rana sylvatica. Abstract | (1) | (2) | (3)

Research scientist, Agriculture and Agri-Food Canada, Ottawa

Tolga Bilgen, Ph.D. Biology 1998.

Differential gene expression response to low temperature exposure in cold hardy insects. Abstract | (1)

Lecturer, University of Washington, Seattle

Justin MacDonald, Ph.D. Biology 1998 | webpage

Enzyme thermal adaptations and signal transduction in ground squirrel hibernation. Abstract | (1) | (2) | (3)

Associate Professor, University of Calgary, Calgary

Kyra Cowan, Ph.D. Chemistry 1998

Reversible phosphorylation control of metabolism during prolonged environmental stress. Abstract | (1) | (2) | (3)

Scientist, Genentech Inc., San Francisco, CA

Brad Thatcher, Ph.D. Biology 1997.

Properties of enzymes from mammalian hibernators: structure-function relationships. Abstract | (1) | (2) | (3)

Vice-President, SynX Pharm Corp., Toronto

Bill Willmore, Ph.D. Biology 1997 | webpage

Molecular adaptation to anoxia and recovery from anoxia in freshwater turtles. Abstract | (1) | (2) | (3)

Associate professor, Carleton University, Ottawa

Jean Grundy, Ph.D. Chemistry 1996.

Antioxidant defenses during estivation in the spadefoot toad, Scaphiopus couchii. Abstract | (1) | (2) | (3)

Product Safety Directorate, Health Canada, Ottawa

Denis Joanisse, Ph.D. Biology 1995 | webpage

Metabolism during overwintering in two species of cold hardy goldenrod gall insects. Abstract | (1) | (2) | (3)

Professor, Laval University, Quebec City

Clark Holden, Ph.D. Biology 1995.

Signal transduction ...and cryoprotectant production in freeze tolerant vertebrates. Abstract | (1) | (2) | (3)

Patent Agent, Osler, Hoskin & Harcourt LLP, Ottawa

Hossein Mehrani, Ph.D. Chemistry 1994

Regulation of glycogen metabolism by protein phosphorylation during stress. Abstract | (1) | (2) | (3)

Professor of Biochemistry, Bagheiatollah Medical Science University, Tehran, Iran

Yanjing Su, Ph.D. Chemistry 1992

Phosphofructokinase from white skeletal muscle and liver of rainbow trout. Abstract | (1) | (2) | (3)

Process development director, Dow Chemical, San Diego, CA

Tom Churchill, Ph.D. Biology 1992 | webpage

Metabolic biochemistry of freeze tolerance in vertebrates. Abstract | (1) | (2) | (3)

Professor, Surgical-Medical Research Unit, University of Alberta Medical School, Edmonton

Bill Plaxton, Ph.D. Biology 1984 | webpages

Metabolic adaptations of marine gastropod molluscs to environmental anoxic stress. Abstract | (1) | (2) | (3)

Professor of Biology & Biochemistry, Queen's University, Kingston

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Former M.Sc. students

Thesis title and abstract, Selected publications

 Former M.Sc. students

Thesis title and abstract, Selected publications

Helen Alyx Holden, M.Sc. Biology 2011

Anuran adaptations to climatic stress: Immune responses and the SMAD family in the wood frog and the African clawed frog. Abstract (1) | (2) | (3)

Katina Sullivan, M.Sc. Biology 2011

Expression pattern of the novel freeze-responsive genes li16, fr10 and fr47 in the wood frog, Rana sylvatica. Abstract (1) | (2) | (3)

Shannon Tessier, M.Sc. Biology 2010

Molecular adaptations of skeletal muscle and cardiac muscle in the hibernating thirteen-lined ground squirrel, Spermophilus tridecemlineatus. Abstract (1) | (2) | (3)

Allan Letourneau, M.Sc. Biology 2010

Phosphorylation of glycolytic enzymes in hibernation. Abstract  (1) | (2) | (3)

Marcus Allan, M.Sc. Biology 2010

Nuclear factor (NF)-kappaB regulation in the hibernating thirteen-lined ground squirrel, Spermophilus tridecemlineatus. Abstract (1) | (2) | (3)

Rabih Roufayel, M.Sc. Biology 2009

Regulation of the Rb-E2F pathway in the freeze tolerant wood frog, Rana sylvatica. Abstract  (1) | (2) | (3)

Oscar Aguilar, M.Sc. Biology 2009

Regulation of the MEF-2 and the SMAD family of transcription factors in the freeze tolerant wood frog, Rana sylvatica    Abstract  (1) | (2) | (3)

Craig Brooks, M.Sc. Biology 2009

Regulation of NF-κB and p53 in the liver and skeletal muscle of the freeze tolerant wood frog, Rana sylvatica. Abstract  (1) | (2) | (3)

Neal Dawson, M.Sc. Biology 2009

Regulation of tail muscle energetics during anoxia in the freshwater crayfish, Orconectes virilis.  Abstract  (1) | (2) | (3)

Judeh Lama, M.Sc. Biology 2008

Regulation of glucose-6-phosphate dehydrogenase and hexokinase in anoxia-tolerant mollusks: role of reversible phosphorylation, Abstract  (1) | (2) | (3)

Ryan Bell, M.Sc. Biology 2008

Regulation of glutamate dehydrogenase in hypometabolic states. Abstract  (1) | (2) | (3)

Mani Mathialagan, MSc Biology 2008

Transcription factor regulation in mammalian hibernation: the thirteen-lined ground squirrel as a model.  Abstract  (1) | (2) | (3)

Jacques Niles, M.Sc. Biology 2007

Freeze tolerant frogs: expression and regulation of transcription factors of the unfolded protein response and the ER-associated degradation.  Abstract  (1) | (2) | (3)

Melanie Bouffard, M.Sc. Chemistry 2007

Involvement of FOXO transcription factors and glycogen synthase kinase 3 in the freeze tolerance capability of the wood frog, Rana sylvatica.  Abstract  (1) | (2) | (3)

Lin Xie, M.Sc. Biology 2007

Antioxidant and anti-apoptotic defenses in the anoxia-tolerant turtle, Trachemys scripta elegans. Abstract  (1) | (2) | (3)

Lin Hui Yao. M.Sc. Chemistry 2007

Profile of FoxO proteins and MnSOD in two cold-hardy insect species exposed to low temperature.  Abstract  (1) | (2) | (3)

Jiayun Zhou, M.Sc. Chemistry, 2006

Regulation of enzymes of energy metabolism – AMP deaminase and creatine kinase – in an anoxia tolerant turtle. Abstract  (1) | (2) | (3)

Guijun (Jeremy)  Zhang, M.Sc. Chemistry 2006

Protein chaperones and winter cold hardiness in insects: heat shock proteins and glucose regulated proteins in freeze-tolerant and freeze-avoiding species. Abstract   (1) | (2) | (3)

Jun Du, M.Sc. Chemistry 2005

Anti-apoptotic and antioxidant defenses in the freeze tolerant wood frog, Rana sylvatica.  Abstract   (1) | (2) | (3)

Ashley Woods, M.Sc. Biology, 2005

Regulation of protein and phospholipid metabolism in the 13-lined ground squirrel, Spermophilus tridecemlineatus and the wood frog, Rana sylvatica.  Abstract  (1) | (2) | (3)

Keqin Yan, M.Sc. Biology 2005

Glucose regulated protein and heat shock protein expression in hibernating mammals.  Abstract   (1) | (2) | (3)

Zhouli Ni, M.Sc. Biology 2000

Antioxidant defense in the hibernating thirteen-lined ground squirrel, Spermophilus tridecemlineatus. Abstract | (1) | (2) | (3)

Li Zhenhong, M.Sc. Biology 2000

 Gene expression supporting freeze tolerance in the wood frog, Rana sylvatica. Abstract | (1) | (2) | (3)

Estatira Sepehr, M.Sc. Chemistry 2002

Effect of fermentation on folate bioavailability. (joint student w S. Brooks) Abstract (1) |

Shahriar Saeedi, M.Sc. Biology 2000

Targeting of calcium calmodulin-dependent protein kinase II to membranes. (joint student w J. Cheetham) Abstract

Tom Pfister, M.Sc. Chemistry 1999

Phosphorylation regulation in two species of cold-hardy goldenrod gall insects. Abstract | (1) | (2) | (3)

Sylvie Lautru, M.Sc. Chemistry 1997

Purification and characterization of hexokinase and pyruvate kinase from Eurosta solidaginis. Abstract

Peggy Schade, M.Sc. Chemistry 1996

Glycogen degradation by alpha-glucosidase. Abstract

Dawn Lobsinger, M.Sc. Biology 1996

Differential gene expression in response to subzero temperatures in the freeze tolerant wood frog Rana sylvatica.  Abstract  | (1)

Tammy English M.Sc. Biology 1995

Enzymes of adenylate metabolism from the skeletal muscle of the hibernating prairie dog. Abstract | (1) | (2)

Steve Greenway M.Sc. Biology 1995

The effect of seasonal change and prolonged anoxia on the metabolism of marine molluscs. Abstract | (1) | (2) | (3)

Marc de la Roche, M.Sc. Chemistry 1995

Metabolic adjustment and biochemical adaptation to torpor in mammalian hibernators. Abstract (1)

Tina Pannunzio, M.Sc. Chemistry 1994

Role of antioxidant defenses in endurance of anoxia and freezing in the marine gastropod Littorina littorea. Abstract | (1)

Donna Douglas, M.Sc. Chemistry 1993

Anoxia induces changes in translatable mRNA during anoxia in Trachemys scripta elegans. Abstract | (1)

Aleixo Muise, M.Sc. Chemistry 1993

Enzymatic regulation of glycerol metabolism in the overwintering gall moth Epiblema scudderiana. Abstract | (1) | (2) | (3)

Elizabeth Russell, M.Sc. Chemistry 1993

Regulation of carbohydrate metabolism in marine molluscs: freezing and anoxia. Abstract | (1) | (2) | (3)

Clark Holden, M.Sc. Biology 1991

The enzymatic control of glycerol metabolism in the freeze avoiding gall insect Epiblema scudderiana. Abstract | (1) | (2) | (3)

Doris Schafhauser, M.Sc. Chemistry 1990

Chicken bone as a support matrix for the immobilization of carbohydrate degrading enzymes. Abstract | (1) | (2) | (3)

Ross Whitwam, M.Sc. Biology 1988 | webpage

The covalent modification of phosphofructokinase and pyruvate kinase in a hypometabolic pulmonate. Abstract | (1) | (2) | (3)

John Duncan, M.Sc. Biology 1988

Glycolytic enzyme binding and metabolic control. Abstract | (1) | (2)

Dave Kelly, M.Sc. Biology 1988

Organ-specific controls of glycolysis in two model systems of facultative hypometabolism mouse. Abstract | (1) | (2)

Ajoy Chakrabarti, M.Sc. Biology 1988

One-step conversion of cellulose to fructose using co-immobilized cellulase, ß-glucosidase and glucose isomerase. Abstract | (1) | (2) | (3)

Roy Cole, M.Sc. Biology 1984

Temperature effect on bivalve anaerobic metabolism. Abstract

Sandra Korycan, M.Sc. Biology 1984

A study of metabolic adaptations of a bivalve mollusc to environmental stresses. Abstract | (1)

Dan Miller, M.Sc. Biology 1983

Hexokinase from the channeled whelk, Busycotypus canaliculatum: physical and regulatory properties. Abstract | (1)

Keith Male, M.Sc. Biology 1982

Metabolic regulation of glutamate dehydrogenase. Abstract | (1) | (2) | (3)